美国老人和中国老人的心脏代谢风险与认知功能之间的关联
Qiao Wu1, Jennifer A Ailshire1, Jung Ki Kim1
1Leonard Davis School of Gerontology, University of Southern California, Los Angeles, California 90089, USA.
概括
心脏代谢风险在美国和中国对认知健康的影响不同. 在美国,较高的心脏代谢风险 (CMR) 与认知能力下降有关,而在中国,教育改变了这种关系.
科学领域:
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
- 神经科学是一个神经科学.
背景情况:
- 心脏代谢风险 (CMR) 是影响认知健康的已知因素.
- 社会经济和医疗背景可以改变CMR与认知之间的关联.
- 发展史和流行病学史的跨文化差异可能导致不同的CMR-认知功能关系.
研究的目的:
- 调查美国和中国老年人心脏代谢风险和认知功能之间的关联.
- 检查教育程度如何影响CMR和认知功能之间的关系在这两个不同的群体.
- 将认知功能的纵向变化与两个国家的CMR水平相比较.
主要方法:
- 在美国 (7,430/4,474) 和中国 (6,108/3,655) 的50岁以上成年人中使用了具有全国代表性的横截面和纵截面样本.
- 采用普通最小平方回归模型来评估CMR和认知功能之间的关系.
- 分析了CMR水平和改变对认知功能的影响,将教育视为调节者.
主要成果:
- 在美国,较高的CMR与更差的认知功能相关 (b=-0.08,p<.016) 和增加的CMR显示与认知衰退 (b=-0.10,p=.055) 有边际显著的关联.
- 在中国整体上,没有观察到CMR和认知功能之间的显著关系.
- 在中国,高等教育水平与更好的认知功能和更慢的衰退有关. 在受过高等教育的中国人中,较高的CMR与更好的认知功能 (b=0.63,p=.013) 和较慢的衰退 (b=0.35,p=.062) 相联系,尽管CMR的快速增加是有害的.
结论:
- 这些发现强调了监测和管理CMR对老年美国人的重要性,以保持认知功能.
- 中国的不同关系,特别是CMR在受过高等教育的人群中的保护作用,表明教育在减轻CMR对认知的影响方面发挥着至关重要的作用.
- 中国的公共卫生战略应侧重于通过教育改善心脏代谢健康,促进健康的生活方式,以应对认知衰老.
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