超声波中的最佳参数连贯平面波组合用于高LPWV估计:对幻影的验证和10个受试者的可行性
Li Xiong1, Yufeng Zhang1, Bingbing He1
1Department of Electronic Engineering, Information School, Yunnan University, Kunming, China.
概括
优化高局部脉冲波速度 (LPWV) 估计的连贯平面波复合 (CPWC) 需要特定的传输角度. 在0.75°间隔的三个倾斜的平面波产生了最可重复的LPWV测量在幽灵和人类.
科学领域:
- 超声波成像 超声波成像
- 生物医学工程 生物医学工程
- 心血管诊断心血管诊断
背景情况:
- 准确的局部脉冲波速度 (LPWV) 估计对于心血管健康评估至关重要.
- 一致的平面波复合 (CPWC) 提供了增强的超声波成像能力.
- 优化CPWC参数对于可靠的LPWV测量至关重要.
研究的目的:
- 确定倾斜平面波的最佳数量和传输角度,以基于CPWC的LPWV估计.
- 用幻影和体内数据评估不同CPWC配置的性能.
- 为准确和可重复的LPWV测量建立参数.
主要方法:
- 使用Verasonics系统与线性阵列探针来获取射频数据.
- 测试了3,5,7和9个倾斜平面波的序列,不同的角度间隔 (粗细).
- 评估了LPWV估计的准确性和可重复性,使用一个状血管幻影和10个健康的人类受试者.
主要成果:
- 最佳配置涉及三个倾斜的平面波,间隔0.75°,在幻影研究中达到最低的变化系数 (CV) 1.84% .
- 这种配置在幻影中产生了13.52 ± 0.08 m/s的LPWV测量.
- 在体内,最佳参数导致LPWV测量为5.49 ± 1.46 m/s,CV为12.35%.
结论:
- 确定的最佳参数在幻影和人体研究中为LPWV测量提供了最佳的重复性.
- 这些发现支持CPWC在临床应用中准确评估LPWV的潜力.
- 建议使用更大的数据集进行进一步的研究,以验证这些发现.
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