孕期早期糖尿病:一个更新
Wesely Hannah1, Rajendra Pradeepa2, Ranjit Mohan Anjana3
1Research Associate, Department of Epidemiology, Madras Diabetes Research Foundation, Chennai, Tamil Nadu, India, Corresponding Author.
概括
在20周之前对孕妇进行早期妊娠糖尿病 (eGDM) 查是有益的. ToBOGM研究表明,早期诊断和治疗eGDM改善了结果,特别是当在14周之前进行查时.
科学领域:
- 产科和妇科 产科和妇科
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 妊娠期高血糖症,包括妊娠期糖尿病 (GDM),是全球重要的健康问题.
- 目前的指导方针建议在怀孕期间对GDM进行查,并转向在头三个月早期检测.
- GDM被分为传统的 (cGDM,24-28周) 或早期的 (eGDM,<20周),对eGDM管理的证据不断演变.
研究的目的:
- 审查关于早期妊娠糖尿病 (eGDM) 诊断和管理的当前理解和证据.
- 要突出关于eGDM的预订妊娠糖尿病治疗 (ToBOGM) 研究的发现.
- 在像印度这样的高负担人口中强调早期GDM查和治疗的重要性.
主要方法:
- 审查关于eGDM的现有文献和证据.
- 随机对照试验的分析,预订妊娠糖尿病治疗 (ToBOGM) 研究.
- 讨论查时间和葡萄糖水平值,以实现最佳的eGDM检测.
主要成果:
- 该ToBOGM研究表明,在诊断和治疗eGDM方面,有明显的好处.
- 在怀孕14周之前接受查的妇女中观察到最优的结果.
- 特定的葡萄糖水平范围 (FPG 95-109 mg/dL,1小时>191 mg/dL,2小时162-199 mg/dL) 显示出更好的结果.
结论:
- 诊断和治疗eGDM是有益的和安全的,得到了最近的试验证据的支持.
- 在第一个产前预约访问时对GDM进行查对于早期检测至关重要.
- 对eGDM的及时干预至关重要,特别是在怀孕期间高血糖率很高的地区.
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