在资源有限的环境中,我们应该如何管理抗菌素耐药性?
Elizabeth A Gulleen1, Margaret Lubwama2
1Infectious diseases physician at the University of Minnesota in Minneapolis and an affiliate investigator at the Fred Hutchinson Cancer Center in Seattle, Washington.
AMA journal of ethics
|May 3, 2024
概括
低收入国家的患者面临更高的抗菌素耐药性感染风险,原因是诊断和治疗的机会有限. 解决这些不平等问题对于改善健康结果和控制耐药性病原体至关重要.
科学领域:
- 全球健康 全球健康
- 传染性疾病 传染性疾病
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 低收入和中等收入国家 (LMICs) 的患者承受着由抗菌素耐药性病原体引起的不成比例的感染负担.
- 获得适当的广谱抗微生物药物对于改善患者的治疗结果和减少LMIC中病原体传播至关重要.
- 在LMICs中存在重大障碍,危及患者获得基本抗菌药物治疗的机会.
研究的目的:
- 检查在诊断,抗微生物药物获取和负担能力方面的不平等对资源有限的环境中的患者结果的影响.
- 突出LMIC中抗菌素耐药性感染患者面临的挑战.
主要方法:
- 审查现有的文献和关于抗微生物药物耐药性,诊断和LMIC中获取LMIC的数据.
- 对社会经济因素对抗生素耐药性感染治疗结果的影响分析.
主要成果:
- 在LMICs中,妥协获得及时和适当的抗微生物药物治疗是一个重大问题.
- 微生物学诊断中的不公平性阻碍了对抗性病原体的准确和快速识别.
- 抗微生物药物负担能力有限进一步加剧了受影响患者的健康状况不佳.
结论:
- 解决诊断,抗微生物药物获取和负担能力方面的系统性不平等是改善LMIC中抗微生物药物耐药性感染患者的护理的关键.
- 需要有针对性的干预措施来克服资源限制,并减少全球抗菌素耐药性的负担.
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