在术后骨盆骨折-尿道损伤患者中优化勃起功能评估模式:引入PFUI pEF PROM
Xianjie Xiu1,2, Ruihang Zhang1,2, Jiahao Lin1,2
1Department of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 600 Yishan Road, Shanghai, 200233, China.
International urology and nephrology
|May 3, 2024
概括
对于骨盆骨折-尿道损伤 (PFUI) 患者的新患者报告结果测量 (PROM) 有效地评估勃起功能. 该工具有助于对患者进行分类,并指导PFUI后勃起功能障碍的治疗.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 安德罗学与人类学
- 医疗信息学 医疗信息学
背景情况:
- 骨盆骨折-尿道损伤 (PFUI) 通常导致勃起功能障碍 (ED).
- 目前对PFUI后ED的评估工具有限.
- 对于PFUI患者,需要一个经过验证的患者报告结果测量 (PROM).
研究的目的:
- 开发和心理验证骨盆骨折-尿道损伤患者报告的勃起功能结果测量 (PFUI pEF PROM).
- 根据勃起功能对PFUI患者进行分类.
- 为了建立一个最佳的评估模式,为手术后勃起功能在PFUI患者.
主要方法:
- 93名PFUI患者接受了切除和初级静脉动脉 (EPA) 尿道成形手术.
- 患者完成了IIEF-5,PFUI pEF PROM和勃起硬度得分 (EHS).
- 进行了心理测量验证,隐性类分析,ROC曲线和单变量分析.
主要成果:
- PFUI pEF PROM显示出高可靠性 (克朗巴赫α = 0.928) 和有效性,与IIEF-5和EHS相关.
- 潜在类分析确定了三个患者子组,截止值为14.5.
- 尿道狭窄的长度,IIEF-5和EHS影响了勃起的潜力;综合评估覆盖了92.5%的患者.
结论:
- PFUI pEF PROM是评估PFUI患者勃起功能的一种可靠和有效的工具.
- 该PROM有助于对PFUI领域的ED进行分层评估,恢复预测和治疗指南.
- 建议采用包括IIEF-5,EHS和PFUI pEF PROM在内的综合评估模式.
相关概念视频
01:28Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors
148
Phosphodiesterase 5 (PDE5) inhibitors are potent enzymes that function to hydrolyze cyclic nucleotides to their corresponding 5' monophosphates. Their unique biochemical properties have been applied in treating Pulmonary Arterial Hypertension (PAH).
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
148
01:20Disorders of the Male Reproductive System
400
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
400
01:17Male Sexual Response: Erection & Ejaculation
2.2K
Sexual stimulation can take various forms, such as physical touch and visual or auditory cues. When this happens, the parasympathetic reflex in the sacral portion of the spinal cord is activated. This reflex stimulates the release of nitric oxide (NO), which then dilates the arterioles in the penis, increasing blood flow to the erectile tissues - the corpora cavernosa and corpus spongiosum.
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
2.2K