肝移植患者感染的流行病学和管理
Waseem Amjad1, Syed Hamaad Rahman2, Thomas D Schiano3
1Gastroenterology and Hepatology, University of Maryland, Baltimore, Maryland, USA.
Surgical infections
|May 3, 2024
概括
肝移植 (LT) 接受者经常面临感染,主要是细菌感染,带来重大风险. 管理抗微生物耐药性和COVID-19等新出现的传染病对于改善患者的治疗结果至关重要.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 移植手术 移植手术
- 传染性疾病 传染性疾病
背景情况:
- 由于手术的进步和免疫抑制,肝移植 (LT) 的结果有所改善.
- 后LT感染仍然是最常见的并发症,影响患者的康复.
- 细菌感染是最常见的,但真菌和病毒感染也经常发生.
研究的目的:
- 审查肝移植接受者感染的流行病学和管理.
- 讨论多药耐药细菌感染带来的挑战.
- 为了解决新出现的传染病,包括COVID-19和麻疹对LT患者的影响.
主要方法:
- 关于肝移植后感染的文献综述.
- 细菌,真菌和病毒传染病原体的分析.
- 讨论抗微生物耐药性和预防策略.
- 包括新出现的传染病数据,这些数据与LT接收者相关.
主要成果:
- 细菌感染是最常见的LT后并发症.
- 多抗药性感染与长时间住院和不良结果有关.
- 在立即LT后的时期,病毒感染很常见.
- 像COVID-19和麻疹这样的新兴传染病带来了独特的挑战.
结论:
- 尽管取得了进展,但LT后感染需要谨慎管理.
- 抗菌药物管理和适当的预防是必不可少的.
- 持续监测和适应新出现的传染性威胁对于LT患者的护理至关重要.
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