儿科下门静脉形形的特征:一个回顾性,多中心的队列研究
Rebecca Calafiore1, Rebecca M Burke1, Andrea Becerril-Gaitan2
1Department of Neurosurgery, Wake Forest University School of Medicine, Winston-Salem , North Carolina , USA.
Neurosurgery
|May 3, 2024
概括
对于儿科动脉静脉形形 (AVM) 的立体射线手术 (SRS) 显示,在下垂体和上垂体AVM之间,可以比较的消灭和出血率. 这表明SRS对于儿童的两个位置都是安全有效的治疗选择.
科学领域:
- 神经外科 神经外科
- 辐射瘤学 辐射瘤学
- 儿科神经学 儿科神经学
背景情况:
- 门下动脉静脉形形 (AVM) 与门上动脉形形相比,具有不同的特征.
- 由于发育因素,儿科AVM需要具体的治疗考虑.
研究的目的:
- 为了研究儿科内动脉动脉瘤的独特特征.
- 评估单次立体性放射性外科手术 (SRS) 对儿科内侧静脉动脉瘤的疗效和安全性.
- 为了比较儿科下门和上门AVM之间的SRS结果.
主要方法:
- 国际放射外科研究基金会数据库的回顾性审查.
- 纳入标准:患有AVM的儿科患者 (<18岁) 用SRS治疗.
- 基线人口统计数据的比较,AVM特征,结果和AVM群体之间的并发症.
主要成果:
- 总共分析了535例儿科AVM (69例在口腔下,466例在口腔上).
- 低静脉AVM显示深部位置,深静脉排水和先前栓塞的患病率更高.
- 两组之间在不良结果,AVM消灭率,SRS后出血或辐射诱导的变化方面没有观察到统计学上显著的差异.
结论:
- 尽管基线特征不同,但立体射线外科手术 (SRS) 对儿科内膜外和上膜外AVM产生了相似的结果.
- SRS 显示了类似的风险概况和治疗效益,适用于婴儿 AVM 的下门和上门.
- 这些发现支持SRS作为儿童AVM的可行治疗方法,无论位置如何.
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