累积缩血压和事件中风类型的变化根据种族和种族
Kimson E Johnson1,2, Hanyu Li3, Min Zhang4
1Department of Health Management and Policy, University of Michigan, Ann Arbor.
JAMA network open
|May 3, 2024
概括
较高的累积平均静脉压 (SBP) 会增加中风风险,包括缺血性中风和脑内出血. 在这项大型美国队列研究中,这些关联并没有因种族或种族而异.
科学领域:
- 心血管流行病学心血管流行病学
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 脑卒中风险受到缩血压 (SBP),种族和种族的影响.
- 累计平均SBP和特定类型的中风之间的关系,以及它在种族和种族群体之间的差异,需要进一步调查.
研究的目的:
- 分析累积平均SBP与第一次发生缺血性中风 (IS),脑内出血 (ICH) 和脑下下出血 (SAH) 的风险之间的关联.
- 探索基于种族和种族的这些协会的潜在差异.
主要方法:
- 从6个美国纵向队列 (1971-2019) 中汇集了个人参与者数据.
- 分析包括38,267名参与者,评估时间依赖的累积平均SBP作为暴露.
- 结果包括时间到第一次发生中风,IS,ICH和SAH.
主要成果:
- 累计平均SBP的10mmHg增加与整体中风 (HR,1.20),IS (HR,1.20) 和ICH (HR,1.31) 的风险增加有关,但不是SAH (HR,1.13).
- 与白人参与者相比,黑人参与者对IS和ICH的风险更高.
- 与白人参与者相比,西班牙裔参与者的SAH风险明显更高.
结论:
- 累积平均SBP与事件中风类型相关,独立于种族和种族.
- 脑卒中预防策略应包括SBP管理,同时应对健康和社会不平等的社会决定因素.
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