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Updated: Jun 27, 2025

Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization
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关于人类血液代谢物全基因组关联研究的协议

Takeshi Iwasaki1, Yoichiro Kamatani2, Kazuhiro Sonomura3

  • 1Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan; Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.

STAR protocols
|May 3, 2024
PubMed
概括

遗传变异会影响血液中的代谢物水平. 这项研究提供了分析管道,以确定对代谢物的遗传影响,有助于理解复杂的特征关联.

关键词:
生物信息学是一种生物信息学.遗传学 遗传学 是一个代谢过程中的代谢.

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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