综合特种药店努力避免口服抗癌药物废弃物的财务影响
Brooke Looney1, Jared Crumb1, Stephanie White1
1Vanderbilt Specialty Pharmacy, Vanderbilt Health System, Nashville, TN.
Journal of managed care & specialty pharmacy
|May 3, 2024
概括
专业药剂师可以减少口服抗癌药物的浪费和成本,通过在补充处方之前审查患者的药物供应和即将到来的后续预约. 这种策略可以避免在昂贵的癌症疗法上不必要的支出.
科学领域:
- 瘤学 药房 实践
- 卫生经济学 卫生经济学
- 药物管理 药物管理
背景情况:
- 口服抗癌药物占医疗保健开支的很大一部分,对患者来说可能很昂贵.
- 对口服抗癌药物的频繁治疗调整往往导致药物浪费.
- 实施尽量减少浪费的策略可以减少患者和付款人的财务负担.
研究的目的:
- 评估审查患者药物库存和即将到来的后续预约对口服抗癌药物的浪费和成本避免的影响.
- 评估综合卫生系统专业药房补充更新流程的有效性.
主要方法:
- 对接受专业药房分发的口服抗癌药物的患者进行了回顾性审查.
- 专业药剂师在处理补充请求之前审查了患者记录以确定药物的适当性和供应.
- 如果患者有足够的药物,则重新补充的更新将被推迟到预定的随访 (例如,提供者访问,实验室测试,成像).
主要成果:
- 推迟补充续期导致大幅节省成本,在12个月内从549,187.03美元到751,994.99美元不等.
- 只有2%的延期更新中药物继续不变,56%的延期更新中药物继续不变,32%的剂量改变,10%的剂量保持或改变.
- 补充更新在159例中被推迟,对135名独特的患者来说.
结论:
- 专门的药剂师干预审查药物供应和后续时间表,有效地减少与口服抗癌药物相关的浪费和成本.
- 在综合卫生系统中,这种主动的方法优化了药物使用和财务管理.
相关概念视频
Factors Influencing Drug Absorption: Presystemic Elimination
214
The pharmacokinetic journey of oral drugs begins with a crucial first pass through the hepatic portal system, called the first-pass effect. This first pass significantly impacts bioavailability — the proportion of a drug that enters systemic circulation and is available for therapeutic action. The primary route sees the drug absorbed by intestinal membranes and then shunted to the liver via the hepatic portal vein. Here, pre-systemic elimination occurs as drugs face metabolism or biliary...
214
Combination Therapies and Personalized Medicine
4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K
Prescription, Nonprescription and Orphan Drugs
722
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
722
Factors Influencing Drug Absorption: Disease States and Pharmacology
503
Multiple disease states can significantly influence the oral drug absorption process by affecting blood flow and the functionality of the gastrointestinal (GI) system. Various GI diseases, including conditions that alter GI motility, such as diarrhea, decreased acid secretions (achlorhydria), and infections, have been associated with reduced drug absorption.
Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...
Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...
503
Factors Affecting Dissolution: Particle Size and Effective Surface Area
823
Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
823
Cancer Therapies
7.6K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.6K


