怀孕妇女的COVID-19感染:婴儿的听觉评估
F Cianfrone1, I Cantore1, C Cazzaniga2
1Otorhinolaryngology Unit, San Filippo Neri Hospital, Rome, Italy.
Journal of neonatal-perinatal medicine
|May 3, 2024
概括
孕妇的COVID-19感染并没有显著影响新生儿的听力. 这项研究发现,与未暴露的婴儿相比,暴露于SARS-CoV-2的婴儿的听力问题风险没有增加.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 新生儿健康 新生儿健康
- 传染性疾病 传染性疾病
背景情况:
- 新出现的证据表明,COVID-19可能会影响尾垂体系统.
- 对SARS-CoV-2垂直传播的可能性及其对胎儿发育,特别是听力的影响仍然存在争议.
研究的目的:
- 研究孕妇在怀孕期间或出生时暴露于COVID-19对后代听力的影响.
- 为了比较COVID-19阳性和COVID-19阴性母亲出生的婴儿之间的听力学结果.
主要方法:
- 一项前性队列研究,涉及新生儿听力查 (暂时引起的耳声发射 - TEOAEs) 在出生和3个月.
- 自动听力脑干反应 (aABR) 在6个月的婴儿中进行,这些婴儿没有通过3个月的查.
- 使用奇平方测试进行统计分析,以比较暴露和未暴露组之间的听力学结果.
主要成果:
- 分析了157名婴儿;16名婴儿出生于COVID-19的母亲. 其中,32个耳朵中的1个 (3.1%) 转移到进一步测试中.
- 在对照组 (未暴露) 中,282个耳朵中有22个 (7.8%) 引用.
- 在COVID-19暴露和未暴露组之间没有观察到听力结果的统计学上显著差异.
结论:
- 孕妇在怀孕期间或出生时感染COVID-19似乎不会显著影响新生儿的听力.
- 建议使用更大的样本大小进行进一步的研究,以更确切地评估COVID-19对婴儿听力的影响.
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