在接受卵巢恶性瘤细胞削减手术的患者中,输血的预测因素
Janina V Pearce1, Jinlei Zhao, Leslie Randall1
1From the Virginia Commonwealth University Health System.
Southern medical journal
|May 3, 2024
概括
在卵巢癌的细胞减少手术中,输血很常见. 较高的估计血液损失 (EBL) 和较低的手术前血红蛋白增加了输血风险,特别是在非拉丁裔白人患者中.
科学领域:
- 妇科瘤学 妇科瘤学
- 手术瘤学手术瘤学
- 输血医学 输血医学
背景情况:
- 卵巢恶性瘤的细胞还原性手术与显著的外科手术期间的血液损失有关.
- 在这些复杂的外科病例中,输血是常见的干预措施.
- 了解影响输血需求的因素对于患者管理至关重要.
研究的目的:
- 为了确定患有卵巢恶性瘤的细胞削减手术的患者的术后输血率.
- 在这个患者群体中描述基线估计血流量 (EBL).
- 为了确定与需要输血相关的术后变量.
主要方法:
- 回顾性队列研究,包括接受细胞减小手术的卵巢恶性瘤患者 (2016-2021年).
- 分析包括t测试,奇平方测试和后勤回归.
- 评估了EBL,手术前血红蛋白和输血风险之间的关联,按种族/种族分层.
主要成果:
- 在44名患者中,有61%接受了术后输血.
- 较高的EBL (442.6毫升 vs 236.8毫升) 和较低的手术前血红蛋白 (10.2 g/dL vs 11.2 g/dL) 与输血有关.
- 增加的EBL与更高的输血风险相关 (OR 3.8),特别是在非拉丁裔白人患者中 (OR 6.1).
结论:
- 在卵巢癌的细胞削减手术中,术后输血是常见的.
- EBL和手术前血红蛋白是输血的关键预测因素.
- 建议采用优化血红蛋白和在手术期间节约血液的策略,同时考虑种族/民族差异.
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