冷静的技术来保护脊髓在胸腔腹腔大动脉置换期间
Taira Yamamoto1, Daisuke Endo2, Yasutaka Yokoyama2
1Department of Cardiovascular Surgery, Juntendo University Nerima Hospital, Nerima-ku, Japan.
The Thoracic and cardiovascular surgeon
|May 3, 2024
概括
这项研究引入了一种新的方法,通过选择性循环冷血来预防大动脉动脉瘤手术期间的脊髓损伤. 这种技术旨在减少再注射损伤,避免患者的永久运动障碍.
科学领域:
- 心血管外科心血管外科
- 神经学 神经学
- 血管外科 血管外科
背景情况:
- 深度低温保护脊髓,但具有侵入性.
- 重灌损伤和是胸腔腹腔大动脉瘤 (TAAA) 修复的重大风险.
- 目前用于减轻这些风险的方法存在局限性.
研究的目的:
- 介绍一种新的方法,以预防TAAA开放修复期间的脊髓损伤.
- 为了避免再注血损伤,在再注血过程中选择性地在高压下向肋间动脉循环冷血.
- 评估该技术在预防永久性运动障碍方面的有效性.
主要方法:
- 选择性循环冷血在高压下到肋间动脉在再注血期间.
- 在接受TAAA开放修复的23名患者中应用.
- 在大动脉紧过程中监测运动唤起的潜力 (MEP).
主要成果:
- 在23名患者中发生了一例死亡.
- 欧洲议会议员在9名患者的大动脉紧过程中失踪.
- 在这9名患者中,有6名患者完全康复,有2名患者>50%康复,有1名患者在3个月后完全康复.
- 没有发生永久的运动障碍.
结论:
- 这种方法有效地防止了再输血损伤.
- 这种技术在TAAA手术后预防残肢方面表现有前途.
- 选择性冷血循环是深度低温的可行替代方案,用于保护脊髓.
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