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Updated: Jun 27, 2025

Immunostaining for DNA Modifications: Computational Analysis of Confocal Images
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原始生殖细胞的DNA脱甲基化和发育需要DNA转化合成

Pranay Shah1, Ross Hill2, Camille Dion3,4

  • 1MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK. pranayshah96@gmail.com.

Nature communications
|May 3, 2024
PubMed
概括

DNA转化合成 (TLS) 对于早期的生殖细胞发育和生育是至关重要的. 像REV1这样的关键TLS因子的丧失,通过防止原始生殖细胞的形成和表观遗传重编程,导致不育.

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