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Updated: Jun 27, 2025

Genome-wide Protein-protein Interaction Screening by Protein-fragment Complementation Assay PCA in Living Cells
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Genome-wide Protein-protein Interaction Screening by Protein-fragment Complementation Assay PCA in Living Cells

Published on: March 3, 2015

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对结构特异性蛋白质与蛋白质相互作用的系统识别

Aleš Holfeld1, Dina Schuster1,2,3, Fabian Sesterhenn1

  • 1Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland.

Molecular systems biology
|May 3, 2024
PubMed
概括

这项研究引入了一种新方法,有限蛋白解质质谱法 (LiP-MS),以确定特定于蛋白质结构的蛋白质相互作用. 这种技术有助于了解疾病机制,揭示了蛋白质相互作用如何在不同状态下发生变化.

关键词:
有限的蛋白质溶解有限的蛋白质溶解质谱测量质量谱测量蛋白质蛋白质 相互作用结构蛋白质组学 结构蛋白质组学结构特异性相互作用

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