在生殖寿命中记录月经周期模式,使用现实世界的数据
Adam C Cunningham1, Lubna Pal2, Aidan P Wickham3
1Flo Health UK Limited, 27 Old Gloucester Street, London, WC1N 3AX, UK. a_cunningham@flo.health.
Scientific reports
|May 3, 2024
概括
月经周期的长度和可变性随着年龄的增长而变化,变得越来越短,变化越来越多,直到绝经前期,那时它们会变长. 像这样的症状减少,而老年人的头痛和失眠增加.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 妇科 妇科 妇科 妇科
- 数据科学在健康中的数据科学
背景情况:
- 月经周期涉及复杂的荷尔蒙和生理变化,影响日常健康.
- 以前的研究往往缺乏多样化的种群,样本大小,以及跨生殖和生命阶段的代表性.
- 了解与年龄相关的月经周期动态对于妇女一生的健康至关重要.
研究的目的:
- 分析月经周期特征和相关症状的年龄相关差异.
- 描述不同年龄组周期长度,变异性和症状记录的动态变化.
- 增强对生殖衰老期间女性生理学的理解.
主要方法:
- 一项大规模的队列研究,利用Flo周期跟踪应用程序 (年龄在18-55岁) 的全球1900多万用户的自我报告数据.
- 分析月经周期和月经周期的长度,它们的标准偏差 (变量),以及症状记录的频率.
- 描述循环特征和症状模式,按使用者的年龄分层.
主要成果:
- 月经周期和月经周期长度表现出明显的与年龄相关的模式,通常随着年龄的增长而缩短和变化.
- 大约在40-44岁 (暗示更年期前期),周期和月经周期会变长,变得更加可变.
- 症状的发病率因年龄而异:老年用户的和减少,而头痛,背痛,压力和失眠增加. 疲劳和乳房疼痛在20-40岁之间达到顶峰,情绪波动在最年轻和最年长的群体中最高.
结论:
- 月经周期的特征和相关症状不是静态的,并且在一个人的生殖寿命中发生显著变化.
- 月经周期的年龄相关变化需要量身定制的医疗保健方法.
- 了解这些动态变化对于改善月经妇女在所有生殖阶段的日常健康和福祉至关重要.
相关概念视频
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