左和右结肠癌手术患者之间的短期和长期结果差异:队列研究
Justas Kuliavas1,2, Kristina Marcinkevičiūtė3, Augustinas Baušys2,4
1Clinic of Gastroenterology, Nephrourology and Surgery, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, LT-03101, Vilnius, Lithuania.
International journal of colorectal disease
|May 3, 2024
概括
与左侧病例相比,右侧结肠癌患者的疾病更为晚期,短期结果相似. 然而,左侧结肠癌 (LCC) 患者的长期存活率显著提高.
科学领域:
- 结肠直肠手术 结肠直肠手术
- 手术瘤学手术瘤学
- 临床结果研究研究
背景情况:
- 有争议的数据存在关于右和左半球切除术后的术后结果.
- 对短期和长期结果的比较分析对于治疗规划至关重要.
研究的目的:
- 为了比较结肠癌的右半球切除术和左半球切除术之间的短期和长期治疗结果.
- 为了澄清现有文学中关于血液切除术结果的差异.
主要方法:
- 一项对1107名因结肠瘤而接受右或左半结肠切除术的患者的回顾性研究 (2014-2018).
- 评估短期结果 (发病率,死亡率,住院,90天再入院) 和长期结果 (总体存活率,无病存活率).
- 多变量考克斯回归分析用于生存分析.
主要成果:
- 右侧结肠癌 (RCC) 患者年龄较大,ASA分数较高,并有更多的并发症.
- 没有发现术后发病率或死亡率的显著差异;在RCC组中,90天的再入院率更高.
- 左侧结肠癌 (LCC) 患者的5年整体存活率和无病存活率明显改善.
结论:
- 右侧结肠癌与老年患者和在呈现时更先进的疾病有关.
- 在右和左半球切除术之间,短期的外科结果是可比的.
- 与右侧疾病相比,左侧结肠癌显示出优越的长期生存结果.
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