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Updated: Jun 27, 2025

Detection of G Protein-coupled Receptor Expression in Mouse Vagal Afferent Neurons using Multiplex In Situ Hybridization
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在APP/PS1小鼠中,寡曼酸激活了肠内分泌 - 阴道 afferent通路

Hua-Shan Gong1,2, Jing-Pei Pan3,4, Fei Guo3

  • 1Songjiang Research Institute, Shanghai Songjiang District Central Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, China.

Acta pharmacologica Sinica
|May 3, 2024
PubMed
概括

寡曼酸 (GV-971) 通过激活肠内分泌细胞和阴道 afferent神经来增强肠-大脑通信,改善阿尔茨海默氏症模型中的认知功能. 这种药物可以通过肠道途径调节大脑功能.

关键词:
在 TRPA1 频道上.肠内分泌细胞 肠内分泌细胞肠-大脑轴 肠-大脑轴寡曼酸是一种酸盐.甜味受体是一种甜味的受体.迷走神经是一种神经.

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