新型精神活性物质 (NPS) 的新兴趋势:设计者THCTHC
Cristian Caprari1,2, Elena Ferri2, Maria Angela Vandelli2
1Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, 41125, Italy.
Journal of cannabis research
|May 3, 2024
概括
本综述详细介绍了娱乐市场上众多类似于大麻素的多四大麻素 (Δ9THC),包括从大麻 (CBD) 衍生出的合成和半合成变体. 这些化合物由于未知的影响和快速的市场演变超过了研究,造成了公共卫生风险.
科学领域:
- 药理学 药理学是指药理学的学科.
- 有机化学 有机化学
- 公共卫生 公共卫生
背景情况:
- Δ9 - 四大麻 (Δ9 -THC) 是大麻的主要精神活性成分,以其与CB1受体的亲和力而闻名.
- 药物化学努力为研究创造强大的D9THC衍生物,无意中导致了它们的娱乐用途.
- 娱乐药品市场上越来越多的THC类大麻素,有些是天然的,有些是合成的或半合成的.
研究的目的:
- 综合审查和记录休市场上可用的THC类大麻素.
- 提供有关这些化合物的化学,合成,药理学和用户报告的精神活性作用的见解.
- 突出公共卫生影响和市场演变与科学研究之间的差距.
主要方法:
- 文献综述和综合科学数据库和在线用户论坛的信息.
- 对娱乐性大麻素的化学结构,合成途径和药理学概况的分析.
- 关于精神活性效应的用户经验报告的汇编.
主要成果:
- 鉴定出了一系列THC类大麻素,包括天然存在的,完全合成的和半合成的化合物,这些化合物来自于合法前体,如CBD.
- 记录了各种合成路线,通常用于规避法律限制.
- 观察到娱乐市场上新化合物的快速出现,超越了科学研究和风险评估.
结论:
- 娱乐市场正在迅速扩大,新的THC类大麻素正在迅速扩大,由于未知的药理效应和不可预测的副作用,这给公共卫生带来了重大挑战.
- 科学研究和监管监督落后于非法药物市场创新的步伐.
- 迫切需要继续进行研究和监测,以了解和减轻与这些新兴精神活性物质相关的风险.
关键词:
设计药物是设计药物.HHCHC HHCHC HHCHC HHC HHC HHC HHC HHC HHC HHC HHC HHC HHC HHC HHC国家安全系统 (NPS) 是一个国家安全系统.合成大麻素是一种合成大麻素.这就是为什么THCTHTHTHTHTHTHTH.更多相关视频
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