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在pemphigus中出现轻度认知障碍
Leila Ghadirzade Arani1, Soroor Advani2, Ghazal Mardani1
1Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
International journal of dermatology
|May 4, 2024
概括
虫患者的轻度认知障碍 (MCI) 率较高,认知测试得分较低,特别是在执行功能方面. 高等教育可能会降低这些人的MCI风险.
科学领域:
- 神经科学是一个神经科学.
- 皮肤病学 皮肤病学
- 自免疫性疾病 自免疫性疾病
背景情况:
- 菲古斯是一种自身免疫性水泡性疾病,与痴呆症有关.
- 轻度认知障碍 (MCI) 通常是痴呆症的前身.
- 之前的研究表明尾虫与痴呆症之间存在关联.
研究的目的:
- 为了确定虫患者中MCI的患病率.
- 为了比较pemphigus患者的认知功能与对照组.
主要方法:
- 一个病例对照研究,涉及80名虫患者和80名对照人群.
- 使用波斯版的蒙特利尔认知评估 (MoCA) 测试来评估认知功能.
- 收集的人口,疾病和药物数据.
主要成果:
- 虫患者中MCI的发生率高于对照组 (37.5%),高于虫患者 (55%).
- 菲古斯患者的总体MoCA得分和执行功能得分较低.
- 教育水平的提高与MCI的可能性降低有关.
结论:
- 虫患者的MCI和执行功能受损的发病率更高.
- 摩卡测试可以帮助识别患有MCI的虫患者,以便进行早期干预.
- 高等教育可能是尾虫中MCI的保护因素.
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