Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Factors Affecting Dissolution: Particle Size and Effective Surface Area01:23

Factors Affecting Dissolution: Particle Size and Effective Surface Area

823
Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
823

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Correction: Kang et al. Energy-Saving Electrospinning with a Concentric Teflon-Core Rod Spinneret to Create Medicated Nanofibers. <i>Polymers</i> 2020, <i>12</i>, 2421.

Polymers·2026
Same author

Core-Sheath Nanofibers From a Modified Coaxial Electrospinning for Transdermal Delivery of Finasteride.

ChemistryOpen·2026
Same author

Fast Dissolving Resveratrol-Polyvinylpyrrolidone Nanofibrous Films Fabricated in Bulk Using a Special Hole Electrospinning Technique.

Polymers·2026
Same author

Electrospun PLA/PVP K90 Biphasic-Release Sublingual Film for Motion Sickness Treatment.

Biomolecules·2026
Same author

Correction: Ning et al. Orodispersible Membranes from a Modified Coaxial Electrospinning for Fast Dissolution of Diclofenac Sodium. <i>Membranes</i> 2021, <i>11</i>, 802.

Membranes·2026
Same author

Waterproof Fabric with Copper Ion-Loaded Multicompartmental Nanoparticle Coatings for Jellyfish Repellency.

Pharmaceutics·2026

相关实验视频

Updated: Jun 27, 2025

Glass-Based Devices to Generate Drops and Emulsions
08:45

Glass-Based Devices to Generate Drops and Emulsions

Published on: April 5, 2022

2.7K

使用电动力原子化进行工程造型,以改善药物输送.

Deng-Guang Yu1, Wenjian Gong1, Jianfeng Zhou1

  • 1School of Materials and Chemistry, University of Shanghai for Science and Technology, Shanghai, China.

Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
|May 4, 2024
PubMed
概括
此摘要是机器生成的。

电动力原子化 (EHDA) 技术可以精确控制微型和纳米产品的形状,显著影响药物释放概况. 本综述探讨了EHDA产生的各种形状,如纳米纤维和纳米颗粒,如何适应各种药物输送应用.

关键词:
有控制释放的释放.药物输送是药物输送的过程.电力旋转是指电力旋转.电气喷是一种电子喷.多室结构的多室结构.形状的形状,形状的形状.

更多相关视频

High-resolution Patterning Using Two Modes of Electrohydrodynamic Jet: Drop on Demand and Near-field Electrospinning
09:16

High-resolution Patterning Using Two Modes of Electrohydrodynamic Jet: Drop on Demand and Near-field Electrospinning

Published on: July 10, 2018

9.7K
Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape
07:38

Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape

Published on: January 8, 2014

8.5K

相关实验视频

Last Updated: Jun 27, 2025

Glass-Based Devices to Generate Drops and Emulsions
08:45

Glass-Based Devices to Generate Drops and Emulsions

Published on: April 5, 2022

2.7K
High-resolution Patterning Using Two Modes of Electrohydrodynamic Jet: Drop on Demand and Near-field Electrospinning
09:16

High-resolution Patterning Using Two Modes of Electrohydrodynamic Jet: Drop on Demand and Near-field Electrospinning

Published on: July 10, 2018

9.7K
Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape
07:38

Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape

Published on: January 8, 2014

8.5K

科学领域:

  • 材料科学与工程 材料科学与工程
  • 纳米技术 纳米技术
  • 制药科学 制药科学

背景情况:

  • 微型和纳米产品的功能性能受到其形状的严重影响,这是一个经常被忽视的因素.
  • 电动力原子化 (EHDA) 技术,包括电和电喷涂,为控制产品形态提供了方便的方法.

研究的目的:

  • 审查由EHDA产生的微型和纳米产品的各种形状.
  • 探索如何利用这些形状来修改和优化药物释放特征以满足各种治疗需求.

主要方法:

  • 关于电动力原子化 (EHDA) 技术 (电,电喷涂) 的文献综述.
  • 分析EHDA产生的各种微型和纳米产品形状,包括线性纳米纤维,圆形微型/纳米粒子和串串珠混合体.
  • 形状的分类及其与药物释放模式的相关性 (脉动性,持续性,双相性,延迟性,pH敏感性).

主要成果:

  • EHDA技术可以产生一系列明确的微型和纳米产品形状.
  • 特定的形状,如线性纳米纤维和球形纳米颗粒,可以设计以实现所需的药物释放动力学.
  • 电纳米纤维的组织和内部结构,除了它们的整体形状外,对于先进的药物输送系统至关重要.

结论:

  • 使用EHDA量身定制微型和纳米产品的形状是控制药物释放的强大策略.
  • 未来的研究应该专注于纳米尺度的形状-性能关系,以推进药物递送技术.
  • 整合形状,尺寸和内部结构分析将推动新型药物输送系统的创新.