在个体患者中,口头记忆网络映射可以预测术后功能障碍
Feng Wang1, Jianxun Ren2, Weigang Cui2
1Department of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Human brain mapping
|May 4, 2024
概括
使用休息状态fMRI的新个性化功能映射技术准确地预测了手术后口头记忆的下降. 这种精确的方法解释了个体大脑网络的变化,改善了外科手术指导,超出了小组级地图集.
科学领域:
- 神经科学是一个神经科学.
- 神经外科 神经外科
- 认知神经学 认知神经学
背景情况:
- 的叶手术可能导致口头记忆力下降.
- 个体大脑网络的变化使使用标准地图集的手术规划变得复杂.
- 精确的手术前测绘对于优化功能结果至关重要.
研究的目的:
- 开发和验证使用静止状态fMRI (rs-fMRI) 进行口头记忆的个性化功能映射技术.
- 评估个性化语言记忆网络 (PVMN) 在预测术后语言记忆缺陷方面的准确性.
- 为了比较个性化映射与小组级地图集的有效性.
主要方法:
- 招募了28名接受手术的耐火性患者.
- 获得了手术前30分钟的rs-fMRI,口头记忆和语言评估.
- 根据个人 rs-fMRI 数据进行划分的PVMN.
- 通过与术后功能障碍和病变重叠相关联来评估PVMN准确性.
主要成果:
- 使用PVMN预测口头记忆下降的准确率为100%,而用小组级地图集的准确率为75.0%.
- 在PVMN的损伤比率和口头记忆下降之间存在显著的相关性 (r = -0.39,p = .038).
- 六名患有超时性病变重叠PVMN的患者表现出选择性口语记忆障碍.
结论:
- 使用rs-fMRI进行个性化功能映射,为个人口语记忆网络提供了宝贵的见解.
- 这种技术在手术中为精确的口头记忆网络映射提供了一个有前途的方法.
- 与标准方法相比,个性化映射可以改善术后口头记忆缺陷的预测.
相关概念视频
01:26Higher Mental Functions of Brain: Learning and Memory
Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or playing an...
01:24Prosopagnosia
Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...
01:14Role of Cerebellum and Prefrontal Cortex in Memory
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the cerebellum's...
01:10Tip-of-the-Tongue Phenomenon
The tip-of-the-tongue (TOT) phenomenon is a cognitive experience characterized by a temporary inability to retrieve specific information from memory despite having a strong feeling of knowing the information. Although individuals cannot access the target word or detail, they frequently recall related elements, such as its initial letter, syllable count, or context. This partial retrieval often causes frustration, as one might recognize a familiar face or know that a name starts with a specific...