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根据生物信息学和机器学习以及实验验证,确定LPCAT1作为克罗恩病的关键生物标志物

Wei Chen1, Zeyan Xu1, Jingjing Jiang1

  • 1Department of Gastroenterology, Zhongda Hospital, Southeast University, Nanjing, 210009, China.

Gene
|May 4, 2024
PubMed
概括

Lysophosphatidylcholine acyltransferase 1 (LPCAT1) 被确定为克罗恩氏病 (CD) 发病的一个关键驱动因素. 向LPCAT1可能为管理CD相关炎症和纤维化提供一种新的治疗策略.

关键词:
生物信息学是一种生物信息学.生物标志物生物标志物克罗恩氏病 克罗恩氏病是什么?在EMT中,EMT是EMT.在 LPCAT1 里.机器学习 机器学习

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In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA (lncRNA)...