在多样化的美国成年人样本中,关于阿片类药物使用障碍的药物的看法
Kaitlyn Jaffe1, Stephanie Slat2, Liying Chen3
1Center for Bioethics and Social Sciences in Medicine, University of Michigan, Ann Arbor, MI, USA; Department of Health Promotion and Policy, University of Massachusetts Amherst, Amherst, MA, USA.
Journal of substance use and addiction treatment
|May 4, 2024
概括
对阿片类药物使用障碍 (MOUD) 药物的负面公众看法很常见,并减少对这些有效治疗方法的偏好. 解决公众的耻辱是改善获得基于证据的护理的关键.
科学领域:
- 成 药物 药物 药物 药物
- 公共卫生 公共卫生
- 健康差异 在健康上的差异
背景情况:
- 治疗阿片类药物使用障碍 (MOUD) 的药物,包括甲,布普伦诺芬和纳尔特雷克松,是安全有效的治疗方法.
- 围绕MOUD的负面公众看法和耻辱感为治疗吸收造成了重大障碍.
- 关于MOUD耻辱的研究主要集中在患者和提供者经验上,对一般公众观点的关注较少.
研究的目的:
- 评估美国成年人对MOUD的看法及其对治疗偏好的影响.
- 探索MOUD的感知如何影响治疗选择,特别是在经历了与毒品有关的歧视的种族化群体中.
主要方法:
- 在2020年10月至2021年1月期间,对1508名多元化的美国成年人进行了调查.
- 该调查衡量了对MOUD和非药物治疗的了解,同意常见的MOUD观念和治疗偏好.
- 多项逻辑回归分析检查了感知和治疗偏好之间的关联,按种族/种族分层.
主要成果:
- 大多数受访者 (66.8%) 知道MOUD,但将其视为阿片类药物的"替代品",并对滥用表示担忧.
- 对于非药物治疗的知识与种族/族裔群体的MOUD偏好正相关.
- 对MOUD滥用的担忧与对特定药物的偏好有负面关联,特别是在白人和拉丁裔受访者中.
结论:
- 关于MOUD的负面公众信念很普遍,并且与对药物治疗的偏好较低有关.
- 这些发现强调了需要采取公共卫生干预措施来解决耻辱和改善对基于证据的MOUD的支持.
- 了解公众的看法对于制定有效策略来提高MOUD可访问性和减少阿片类药物使用障碍的流行率至关重要.
更多相关视频
相关概念视频
Drug Abuse and Addiction: Pharmacological Phenomena
467
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
467
Opioid Analgesics: Synthetic and Semisynthetic Opioids
287
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
287
Opioid Analgesics: Morphine and Other Natural Cogeners
242
Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
242
Prescription, Nonprescription and Orphan Drugs
722
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
722
Substance Use Disorders Affecting Sleep
166
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
166
Analgesia and Pain Management
585
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
585


