基于动物浮游生物的不良结果途径:评估水生环境中的内分泌干扰化合物的工具
Muhammad Raznisyafiq Razak1, Sze Yee Wee2, Fatimah Md Yusoff3
1Department of Environment, Faculty of Forestry and Environment, Universiti Putra Malaysia, 43400, UPM Serdang, Selangor, Malaysia.
Environmental research
|May 4, 2024
概括
本综述总结了动物浮游生物如何作为生物指标,以了解水生环境中内分泌干扰化合物 (EDC) 引起的不良结果途径 (AOP). 基于动物浮游生物的AOPs有助于风险评估和化学品监管.
科学领域:
- 生态毒理学 生态毒理学
- 环境科学 环境科学
- 水生毒理学 水生毒理学
背景情况:
- 内分泌干扰化合物 (EDC) 存在生态风险,特别是在水生生态系统中.
- 识别和监管EDC是生态毒理学的优先事项.
- 动物浮游生物被公认为标准化和验证的生物指标.
研究的目的:
- 审查有关EDCs的基于动物浮游生物的不良结果途径 (AOPs).
- 专注于淡水动物浮游生物作为生态毒理学评估中的生物指标.
- 突出动物浮游生物在理解EDC毒性机制中的作用.
主要方法:
- 基于动物浮游生物的AOPs的文献综述.
- 对动物浮游生物中EDC暴露的案例研究的分析.
- 在动物浮游生物-AOPs中识别分子启动事件 (MIEs) 和关键事件 (KEs).
主要成果:
- 基于动物浮游生物的AOP提供了对EDC内分泌干扰的见解.
- 案例研究表明动物浮游生物在AOP发展中的实用性.
- 讨论数据来源,实验方法和挑战.
结论:
- 基于动物浮游生物的AOP对于了解EDC影响非常有价值.
- 该AOP框架巩固了EDC的毒理学知识.
- 这种方法增强了风险评估和化学品监管策略.
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