身体活动和败血症的发生率:在400万成年人中进行了一项为期10年的观察研究
Kyoung Hwa Lee1, Eun Hwa Lee1, Kyu-Na Lee2
1Division of Infectious Disease, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
概括
定期体育活动 (PA) 与败血症风险降低有关,特别是在老年人中. 适度PA显示出最低的败血症发病率和死亡率,表明其作为预防策略的潜力.
科学领域:
- 老年学与公共卫生
- 流行病学 流行病学
- 预防医学 预防医学
背景情况:
- 由于人口老龄化,败血症发病率正在上升.
- 身体活动 (PA) 提供健康益处,可以作为败血症预防策略.
- 目前没有直接的抗败血症药物可用于个性化预防.
研究的目的:
- 调查身体活动水平 (强度,持续时间,频率) 与败血症发病率之间的关联.
- 检查体育活动和败血症后的死亡率之间的关系.
- 为了确定最佳的PA水平来降低败血症风险.
主要方法:
- 大规模的,回顾性,使用韩国国家医疗保险服务数据的纵向队列研究.
- 根据代谢等价物 (METs) -Min/Week. 分类为非PA,轻度,中度,严重和极端的PA.
- 多变量回归分析调整了人口统计和临床因素.
主要成果:
- 中度血压 (500-1000 METs-Min/Week) 与最低的败血症发病率 (1.56/1000人/年) 和降低的风险 (aHR 0.73) 有关.
- 在65岁以上和前吸烟者中,中度PA组中,败血症的发生率明显较低.
- 与非PA组相比,参与PA的参与者在败血症后的全因死亡率明显较低.
结论:
- 身体活动与败血症风险较低有关,特别是在老年人中.
- 适度的身体活动显示出对败血症的保护作用.
- 空气性PA在败血症预防中的作用需要在临床指南中考虑.
相关概念视频
Healthcare Associated Infections II: Preventive Measures
2.6K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.6K
Factors Affecting the Risk of Infection
11.8K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.8K
Steps in Outbreak Investigation
124
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
124


