短期中等强度运动对老年人血清代谢组的影响:试点随机对照试验
Jie Jun Wong1, Jien Sze Ho1,2, Louis L Y Teo1,2
1National Heart Centre Singapore, Singapore, Singapore.
Communications medicine
|May 4, 2024
概括
中等强度的运动训练改变了中年成人血清代谢,减少了长链乙卡尼丁. 这些发现表明,运动会影响与心血管健康相关的代谢途径.
科学领域:
- 心血管生理学心血管生理学
- 代谢学 代谢学 代谢学
- 运动科学 运动科学
背景情况:
- 以前的研究发现了与心肌放松受损相关的血清代谢组变化.
- 这项研究研究了运动干预对健康成年人血清代谢学的影响.
研究的目的:
- 为了评估12周的中等强度运动计划对无心血管疾病的社区成年人血清代谢学的影响.
主要方法:
- 一个前性的,并行组,随机对照试验试验,涉及30名中年成人.
- 参与者被随机分配到12周的中等强度运动干预 (有氧和力量训练) 或对照组.
- 干预前后收集血清样本进行代谢分析.
主要成果:
- 与对照组相比,在运动组中观察到长链乙利尼丁C20:2-OH/C18:2-DC的显著减少.
- 在两组中,特定代谢物 (氨酸,酸盐,C20:3) 与心脏功能参数 (左心室质量指数,侧面e',E/e'比率,E/A比率) 有相关性.
结论:
- 运动干预表明对血清代谢概况的影响,特定的乙卡尼丁显示出显著的变化.
- 这些试点观测突出了运动,血清代谢物和心脏功能之间的潜在联系,需要进一步研究预防策略的代谢途径.
更多相关视频
09:19Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice
Published on: February 2, 2019
9.8K
14:39Semi-Targeted Ultra-High-Performance Chromatography Coupled to Mass Spectrometry Analysis of Phenolic Metabolites in Plasma of Elderly Adults
Published on: April 22, 2022
3.9K
相关概念视频
Exercise and Cardiovascular Response
792
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
792
Exercise and Cardiac Output
1.0K
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
Sustained exercise increases the muscles' oxygen demand, which can be...
1.0K
Exercise and Muscle Performance
1.4K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
1.4K
