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Updated: Jun 27, 2025

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转录因子SOX6通过转录因子LIN28B基因的转录抑制

Valentina Pastori1, Gianluca Zambanini2,3,4, Elisabetta Citterio1

  • 1Dipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano-Bicocca, Milan, Italy.

Scientific reports
|May 4, 2024
PubMed
概括

转录因子SOX6抑制LIN28B的表达,影响胎儿/成人基因切换和癌细胞增殖. 这种SOX6介导的LIN28B下调可能通过阻断细胞分裂来限制瘤生长.

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