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对动脉瘤下关节出血后结果的性别差异的比较:倾向性得分匹配分析

Yuwei Han¹, Bingying Zhang¹, Xin Qi¹

¹Department of Neurology, General Hospital of Northern Theater Command, NO.83, Wenhua Road, Shenhe District, Shenyang, 110016, Liaoning, China.

|May 4, 2024

概括

患有动脉瘤下arachnoid出血 (aSAH) 的女性患者经历了更糟糕的结果,有较高的延迟脑缺血和脑水症. 这表明女性可能在aSAH后更容易受到这些并发症的影响.

科学领域:

神经学神经学
神经外科神经外科
临床结果研究研究

背景情况:

动脉瘤下arachnoid出血 (aSAH) 的结果的性别差异尚未得到充分证实.
研究这些差异对于了解患者的预后至关重要.

研究的目的:

调查aSAH患者预后中的性别差异.
确定与aSAH患者不良结果相关的风险因素.

主要方法:

对665名aSAH患者的回顾性分析 (2020年4月 - 2022年1月).
1:1倾向分数匹配 (PSM) 用于比较男性和女性队列.
修改后的兰金尺度 (mRS) 评估了释放后3个月的结果.

主要成果:

女性患者年龄较大,占研究队列的大多数 (63.8%).
在PSM之后,女性在3个月后表现出显著更高的延迟脑缺血 (DCI),脑水和不利的mRS分数 (≥2) 的比率.
年龄,性别,吸烟,高亨特·赫斯等级,高mFisher分数,DCI和水头是预后不佳的独立风险因素.

结论:

与男性患者相比,患有aSAH的女性患者的预后更差.
对DCI和水头的脆弱性增加可能会导致女性的治疗结果较差.
调查结果强调了在SAH管理中考虑性别特异因素的重要性.

关键词:

动脉瘤下arachnoid出血动脉瘤下arachnoid出血动脉瘤下arachnoid出血一个女人,一个女人.结果结果的结果.倾向性得分匹配的匹配方法

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