帕金森病中冷漠和冲动控制障碍的同时发生:在多种措施中存在差异
Bonnie M Scott1,2, Robert S Eisinger3,4, Roshan Mara1
1Department of Neurology, Dell Medical School, University of Texas at Austin, Austin, TX, USA.
概括
无动于衷和冲动控制障碍 (ICD) 在帕金森病 (PD) 中同时发生,但其发生率取决于所使用的测量工具. 在PD患者的不同冷漠度测量之间存在有限的一致性.
科学领域:
- 神经学 神经学
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
背景情况:
- 无动于衷和冲动控制障碍 (ICD) 在帕金森病 (PD) 中很常见.
- 在PD中,冷漠和ICD之间的关系尚未完全理解.
- 仪器的选择可能会影响观察到这些条件的同时发生.
研究的目的:
- 调查帕金森病中冷漠和ICDs的同时发生是否取决于所使用的特定测量仪器.
- 评估三种不同的冷漠度指标的同时有效性.
- 检查PD中冷漠和ICD之间的相互关系.
主要方法:
- 97名患有特异性帕金森病 (PD) 的个人参与了这项研究.
- 参与者填写了帕金森病评分尺度 (QUIP-RS) 中冲动-强迫性障碍问卷.
- 进行了三项冷漠度测量:冷漠度量表,里尔冷漠度评级量表和MDS-UPDRS第4项.
主要成果:
- 超过一半的参与者 (51.5%) 在至少一项测量中满足了无动于衷的标准.
- 在不同措施中观察到冷漠和ICD同时发生的显著差异.
- 只有很小的百分比 (4.3%) 在所有三个冷漠度指标上都有临床上较高的得分.
结论:
- 无动于衷和ICDs在帕金森病中同时发生,但程度因无动于衷评估工具而异.
- 在评估的冷漠度指标中存在有限的并发有效性.
- 研究结果强调了仪器选择对于未来研究共享病理生理学和PD临床试验的重要性.
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