用手术内超声波 (SEE U) 进行外科疏散:一项随机对照试验
Paul P Smith1, Versha Cheed2, Lee Middleton2
1Birmingham Women's & Children's Hospital and University of Birmingham, Birmingham, UK.
概括
术内超声波并没有显著减少手术流产管理中的并发症. 较大的试验比较超声波使用与没有超声波是可行的.
科学领域:
- 生殖医学 生殖医学
- 手术创新 在外科创新.
- 临床试验 临床试验
背景情况:
- 手术治疗流产是一种常见的程序.
- 由于手术切除受孕产物,可能会出现并发症.
- 在手术期间的指导可能会改善结果.
研究的目的:
- 评估大型随机对照试验 (RCT) 的可行性.
- 为了确定手术内超声波是否可以减少流产外科手术后的早期和晚期并发症.
- 评估过程结果,包括查,随机化和可接受性.
主要方法:
- 进行了一项前性的,多中心的,随机的,开放的临床试验.
- 经过手术流产管理的16岁以上妇女被随机分类.
- 参与者接受了持续的手术内超声波或没有超声波指导.
主要成果:
- 59名女性被随机分配; 75%的转化率用于试验入学.
- 综合结果 (不成功的手术或并发症) 发生在19%的无超声波患者和25%的超声波患者中.
- 除了COVID-19相关的宫镜取消,结果是没有超声波的19%,超声波的20%.
结论:
- 一个大规模的RCT比较流产的手术管理与无手术超声波是可行的.
- 这项试点研究为未来优化流产管理研究提供了基础.
- 需要进一步的研究来证实手术内超声波的作用.
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