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实施外科手术期间血糖监测和胰岛素输注协议可以降低接受选择性切割的糖尿病患者的术后感染率:一项观察性研究
Alexander Kulikov1, Yulia Krovko1, Timur Zagidullin1
1Burdenko National Medical Research Center of Neurosurgery, Moscow, Russia.
概括
实施血糖监测和胰岛素输注的标准化方案显著减少了骨切割患者的术后感染. 这种方法有效地控制了严重的高血糖,降低了并发症风险.
科学领域:
- 神经外科 神经外科
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
背景情况:
- 严重的外科手术期间高血糖症 (SH) 是切术后并发症的已知危险因素.
- 为了减轻这种风险,建议采用标准化临床方案来监测血糖度 (BGC) 和静脉注射 (IV) 胰岛素输液.
- 这项研究评估了这种协议对选择性切割患者手术后感染率的影响.
研究的目的:
- 评估经手术期间血糖控制标准化方案在减少骨切除术后的术后感染方面的有效性.
- 评估计划的BGC监测和IV胰岛素输注对感染率的影响.
主要方法:
- 一项前性观察性研究,涉及42名接受选择性切割的患者.
- 实施计划的BGC监测和IV胰岛素输注用于手术期间的SH.
- 与使用零星BGC监测和SH皮下胰岛素的对照组进行比较.
主要成果:
- 在前组中,只有1名患者 (2%) 患有传染性并发症 (肺炎).
- 与对照组相比,观察到手术后感染风险的统计显著下降 (OR = 0.08,p = 0.02).
- 该方案有效地预防了严重的高血糖和低血糖 (BGC < 70 mg/dl).
结论:
- 定期的BCC监测和低剂量胰岛素输注方案可以降低骨切割患者的术后感染率.
- 需要进一步的研究来确定协议实施和改善结果之间的因果关系.
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