红色水果中发现的主要的抗氧化活性:一个体外和体内研究
Ana C Gonçalves1, Amílcar Falcão2, Gilberto Alves3
1CICS-UBI-Health Sciences Research Centre, University of Beira Interior, 6201-506 Covilhã, Portugal; CIBIT-Coimbra Institute for Biomedical Imaging and Translational Research, University of Coimbra, 3000-548 Coimbra, Portugal.
Food chemistry
|May 5, 2024
概括
红色水果的有显著的抗氧化活性. 氨酸和其他化合物有效地中和有害基因,支持它们在新产品中的使用.
科学领域:
- 植物化学 植物化学
- 营养保健品 营养保健品
- 食品科学 食品科学 食品科学
背景情况:
- 红色水果中丰富的化合物具有众所周知的健康益处.
- 了解它们的特定抗氧化能力对于产品开发至关重要.
研究的目的:
- 为了评估红色水果中的23种主要的抗氧化活性.
- 评估它们对三个关键自由基的有效性:DPPH,氧化 (NO) 和超氧化 (O2-).
- 通过分子对接和ADME研究,探索有前途的化合物的生物潜力.
主要方法:
- 对抗氧化能力的测定对1,1-二-2-皮克里利水 (DPPH),氧化 (NO) 和超氧化 (O2-) 基进行了测试.
- 对精选的化合物进行了分子对接和吸收,分布,新陈代谢和分泌 (ADME) 研究.
主要成果:
- 安托西亚宁, (-) - 甲,和甲 3-O-rutinoside 显示高活性对 DPPH 基.
- 安索亚宁, (-) - 甲,奎尔丁3-O-葡萄糖化物和咖啡酸对NO基有很强的作用.
- 奎尔酸甘氨酸及其衍生物对超氧化激素表现出最强的活性.
结论:
- 红色水果中的化合物具有显著的抗氧化特性.
- 特定的化合物对各种自由基具有差异性的有效性.
- 这些发现支持将红色水果的元素纳入功能性食品和营养食品中.
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