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Updated: Jun 22, 2026

Micro-Mechanical Characterization of Lung Tissue Using Atomic Force Microscopy
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强血性肺组织的机械和形态表征

Benjamín Villa1, Benjamín Erranz2, Pablo Cruces3

  • 1Department of Structural and Geotechnical Engineering, School of Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, Vicuña Mackenna 4860, Santiago, Chile; Institute for Biological and Medical Engineering, Schools of Engineering, Medicine and Biological Sciences, Pontificia Universidad Católica de Chile, Vicuña Mackenna 4860, Santiago, Chile.

Acta biomaterialia
|May 5, 2024
PubMed
概括

肺气会损害肺组织,导致气膜扩大. 这项研究表明,虽然整个肺机理保持稳定,但肺组织特性发生显著变化,这表明早期肺重塑.

关键词:
构成模型的建构模型.肺机械学 肺机械学肺部形态测量 肺部形态测量 肺部形态测量肺肺复发症 肺肺复发症组织力学是组织力学.

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Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.