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Updated: Jun 27, 2025

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
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Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells

Published on: October 27, 2020

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潜伏转化生长因子β-结合蛋白1/转化生长因子β1复合驱动对黑色素瘤中的ERK5向对抗瘤效应

Alessandro Tubita1, Alessio Menconi1, Zoe Lombardi1

  • 1Department of Clinical and Experimental Biomedical Sciences, University of Florence, Florence, Italy.

The American journal of pathology
|May 5, 2024
PubMed
概括

抑制黑色素瘤中的细胞外信号调节激酶5 (ERK5) 抑制潜伏转化生长因子β结合蛋白1 (LTBP1) 和转化生长因子β (TGF-β1). 这促进了瘤抑制和更好的患者存活率,特别是在抗PD1疗法.

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