工作记忆训练后休息状态功能连接的变化,在反复负面思维的个体中
Jessica Bomyea1, Shirley Feng2, Raeanne C Moore3
1Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, San Diego, California; Department of Psychiatry, University of California San Diego, San Diego, California.
概括
工作记忆训练改善了重复负面思维 (RNT) 个体的休息状态功能连接 (rsFC). 这些神经变化与减少RNT症状有关,这表明潜在的治疗益处.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 临床心理学 临床心理学
背景情况:
- 重复的负面思维 (RNT) 在情绪,焦虑和创伤障碍中很普遍.
- 工作记忆调节受损是RNT的潜在原因.
- 工作记忆训练可能为RNT提供治疗途径.
研究的目的:
- 研究工作记忆训练对休息状态功能连接 (rsFC) 对高RNT个体的影响.
- 确定RSFC的变化是否与RNT症状严重程度的改善相关.
主要方法:
- 来自随机对照试验的数据的二次分析,将工作记忆训练 (n=42) 与等候名单对照 (n=23) 进行比较.
- 检查了静止状态前后fMRI数据,重点关注默认模式网络 (后侧环状皮质) 和前侧对面网络 (背侧前额皮质) 之间的连接.
主要成果:
- 与对照组相比,工作记忆训练组在后带带皮层和前额/骨区域之间增加了rsFC.
- 背带皮层和上额皮层之间更大的连接性增加与显著的RNT症状减少相关.
结论:
- 工作记忆训练有效调节经历RNT的个体的静止状态神经电路.
- 观察到的神经电路变化支持工作记忆训练对跨诊断RNT症状的潜在临床实用性.
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