评估氧化消毒剂的稳定性和杀菌效果
L Brown1, A Marshall1, L Conway1
1Fellows Research Centre, Gama Healthcare Ltd, North Dean Business Park, Stainland Rd, Greetland, Halifax, UK.
氧化消毒剂,包括基剂,在脏条件下显示效率降低. 然而,甲酸保持了稳定性和杀菌效果,这对于预防医疗相关感染至关重要.
科学领域:
- 环境微生物学环境微生物学
- 感染控制的方法是感染控制.
背景情况:
- 医疗保健环境是病原体传播的重要储库.
- 标准EN 17126:2018提供了一个框架,用于测试使用现实的土壤负载的杀虫剂产品.
研究的目的:
- 评估氧化消毒剂的化学稳定性和杀菌效果.
- 为了评估模拟清洁与医疗污秽条件下的性能.
主要方法:
- 消毒剂对Clostridioides difficile内体进行了测试,使用EN 17126:2018.
- 在模拟土壤的存在下测量了化学稳定性和活性剂度.
- 统计分析比较了在干净和脏条件下的表现.
主要成果:
- 基于的消毒剂 (二氧化,低酸) 在脏的条件下表现出较低的稳定性和有效性.
- 乙酸表现出一致的稳定性和杀菌效果,即使在医学土壤的存在下也是如此.
- 对于释放剂,性能取决于度.
结论:
- 环境污染清除效果不佳,造成医疗机构中病原体传播的风险.
- 甲酸在具有挑战性的临床环境中显示出可靠消毒的前景.
- 消毒剂的选择应考虑在有机物质存在的情况下的有效性.
更多相关视频
11:47Evaluation of the Efficacy of Organic Peroxyacids for Eradicating Dairy Biofilms Using an Approach Combining Static and Dynamic Methods
Published on: December 9, 2022
07:07Controlled-release of Chlorine Dioxide in a Perforated Packaging System to Extend the Storage Life and Improve the Safety of Grape Tomatoes
Published on: April 7, 2017
相关概念视频
Methods of Sterilization II: Chemical Methods
Using chemical sterilization rather than heat to clean out equipment is recommended. It eradicates and removes all bacteria,...
Methods of Sterilization I: Physical Methods
Steam sterilization uses non-toxic, low-cost moist heat in the form of saturated steam under pressure, which is fast, microbicidal, and sporicidal, and quickly warms and penetrates fabrics. Autoclaves, or steam sterilizers, expose each item to direct steam contact for a predetermined time at the necessary...
Oxidation of Phenols to Quinones
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...
Oxidation of Alcohols
The process of oxidation in a chemical reaction is observed in any of the three forms:
Cleaning, Sterilization, and Disinfection
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
Oxidations of Aldehydes and Ketones to Carboxylic Acids
Aldehydes readily undergo oxidation in strong oxidizing agents such as potassium permanganate and chromic acid. The oxidation can also be carried out using mild oxidizing agents such as silver oxide. In fact, aldehydes can be easily oxidized...
