与宿主相关的低流行性胃炎:流行病学和临床表征
Robert M Genta1, Massimo Rugge2
1Inform Diagnostics, Irving, TX, USA; Departments of Pathology and Medicine (Gastroenterology), Baylor College of Medicine, Houston, TX, USA.
概括
发病率低的胃炎类型,如乙酸性胃炎和淋巴细胞性胃炎,是鲜为人知的,但与其他疾病有关. 增加检测可以使这些罕见诊断的患者受益.
科学领域:
- 胃肠病学 胃肠病学
- 病理学 病理学 病理学
- 流行病学 流行病学
背景情况:
- 专注于罕见的"与宿主相关的,低患病率的胃炎",包括埃索诺菲尔性 (EoG),淋巴细胞性 (LyG),原性 (CollG) 和颗粒性胃炎 (GrG).
- 解决了在RE.GA.IN共识会议上确定这些条件的更好描述的需要.
研究的目的:
- 评估EoG,LyG,CollG和GrG的临床流行病学特征.
- 将这些罕见的胃炎与一般患者群体 (对照组) 进行比较.
主要方法:
- 从临床病理学数据库中提取了被诊断为EoG,LyG,CollG和GrG的患者数据.
- 与对照组比较人口统计,临床/内镜特征,相关疾病和临床意识.
主要成果:
- 分析了1,781,005名患者;罕见的胃炎很少被诊断出 (<1:1,000).
- 确定了特定的关联:EoG与乙性食道炎 (EoE),LyG与腹腔疾病,CollG与微观结肠炎,GrG与克罗恩病.
- 临床意识非常低 (<1:10,000),没有明显的诊断临床表现.
结论:
- 这些胃炎的诊断依赖于组织病理学,它们的特征很差.
- 这些情况在临床上被忽视,但它们的关联可以表明其他严重疾病,如EGID,乳和克罗恩病.
- 增加这些胃炎的检测和表征可能会改善患者的治疗结果.
相关概念视频
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