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一种新的定量方法来评估腰椎退化:MRI直方图分析分析

Zhaohui Li¹, Yurui Wu², Mengyang Liu²

¹Department of Spine Surgery, Hebei Medical University Third Hospital, 139 Ziqiang Road, Shijiazhuang, 050051, China.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

|May 5, 2024

概括

核磁共振成像图分析为评估腰椎变性 (LDD) 提供了可靠和客观的方法. 这种技术与Pfirrmann分类有很强的相关性,并且在各种成像条件中显示出良好的一致性.

科学领域:

放射学放射学是一门学科.
医学成像分析医学成像分析
生物医学工程生物医学工程

背景情况:

腰椎间盘退化 (LDD) 是一种影响脊柱健康的常见疾病.
传统的LDD评估依赖于像Pfirrmann方法这样的主观分类.
需要客观和定量工具来评估LDD.

研究的目的:

为了评估腰椎间盘退化 (LDD),使用常规MRI序列上的MRI直方图分析.
为了确定MRI组图分析与已建立的Pfirrmann分类之间的相关性.
通过全面的协议研究来评估MRI组图分析的客观性和稳定性.

主要方法:

包括来自133名受试者的腰部MRI图像.
使用Pfirrmann等级对LDD进行分类,并通过MRI历史图分析测量峰值分离值.
两种方法之间的相关性分析,切割值的确定,以及对相互解决,相互观察,相互ROI和相互切割协议的类内相关系数 (ICC) 分析.

主要成果:

在峰值分离值和Pfirrmann等级之间发现了强烈的相关性 (r = -0.847).
对于压缩分辨率,除了最低分辨率 (ICC = 0.533) 之外,对压缩分辨率的内部分辨率协议 (ICCs 0.822-0.916) 很好或很好.
优秀的观察者间 (ICC = 0.982) 和ROI间 (ICC = 0.915) 协议,对相邻的切片有良好的切片间协议.

结论:

常规序列上的MRI组图分析与LDD评估的Pfirrmann分类有很强的相关性.
该方法在各种协议场景 (解决方案间,观察者间,ROI间,切片间) 中表现出良好的客观性和稳定性.
核磁共振成像图分析为评估LDD提供了有效,客观和定量工具,扩大了其临床应用.

关键词:

腰椎盘退化腰椎盘退化核磁共振成像图分析分析磁共振成像技术磁共振成像技术定量评价定量评价定量评价定量评价

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