对大规模前列腺癌查的成本效益分析
Hiro Farabi1, Najmeh Moradi2, Aziz Ahmadzadeh3
1Barts and the London Pragmatic Clinical Trials Unit, Centre for Evaluation and Methods, Wolfson Institute of Population Health, Queen Mary University of London, London, UK. h.farabi@qmul.ac.uk.
Cost effectiveness and resource allocation : C/E
|May 5, 2024
概括
使用前列腺特异抗原 (PSA) 和数字直肠检查 (DRE) 的前列腺癌查对40-69岁的男性来说具有成本效益. 40-49岁的年龄组显示了最高的净益,证明了有针对性的查计划的合理性.
科学领域:
- 卫生经济学 卫生经济学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 前列腺癌 (PCa) 给全球的健康和经济带来了巨大的负担.
- 有效的大规模查策略对于早期检测和管理至关重要.
- 本研究评估了伊朗PCa查的经济可行性.
研究的目的:
- 确定伊朗PCa查的净成本效益指数 (NCBI).
- 为了比较不同查策略的成本效益.
- 为PCa选计划的资源分配提供信息.
主要方法:
- 用于计算四个年龄组 (40+) 的NCBI的决策分析模型.
- 评估的查策略:单独PSA与PSA与数字直肠检查 (DRE).
- 1402名PCa患者数据的回顾性分析,包括直接的医疗/非医疗成本和支付意愿 (WTP).
主要成果:
- 联合PSA和DRE策略具有成本效益,每例可节省高达3美元.
- 70岁以上的男性的查在经济上是不合理的 (负NCBI).
- 40-49岁的年龄组获得了最高的净收益 (13.81美元-13.54美元).
结论:
- 用PSA和DRE进行前列腺癌查对于40-69岁的男性来说,经济上是合理的.
- 决策者应该根据年龄和预算优先分配资源.
- 支付意愿,特别是在年轻年龄组,可以支持查举措.
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