在儿童和青少年中,初级甲状腺功能障碍症的可变表现和结果
Debaditya Das1, Mainak Banerjee1, Anish Kar1
1Department of Endocrinology, I.P.G.M.E.R and S.S.K.M Hospitals, Kolkata, India.
概括
儿童和青少年的原发性副甲状腺症 (PHPT) 呈现独特,通常有严重的症状,如性特征. 提高临床警和测试对于在年轻患者中诊断这种独特疾病至关重要.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 代谢性骨疾病 代谢性骨疾病
- 临床病例系列 临床病例系列
背景情况:
- 初级偏甲状腺症 (PHPT) 与成人相比,在儿童和青少年群体中表现出明显的临床表现.
- 儿童的独特和严重的症状需要差异化的诊断和管理方法.
研究的目的:
- 突出PHPT在儿童和青少年中的特殊表现.
- 将儿科病例系列中的临床数据与现有文献进行比较.
- 在19岁以下的个体中识别PHPT的特定特征.
主要方法:
- 介绍了一系列病例,涉及5名患有PHPT的儿科和青少年患者.
- 对该中心数据与已发表的文献进行比较分析.
- 描述相关年龄组中先前报告的病例中突出的表现特征.
主要成果:
- 在年轻人中,PHPT具有独特的特征,包括肌性表现和严重程度增加.
- 观察到的特定表型包括尽管维生素D纠正,但仍然存在持续性狂风性特征,胰腺炎和双边结石病.
- 无法解释的精神疾病异常也可能呈现症状.
结论:
- 儿童和青少年的PHPT应该被视为与成人PHPT不同的实体.
- 临床警对于识别PHPT至关重要,特别是在性特征持续存在时,或出现胰腺炎或精神问题等不寻常症状时.
- 血清和尿液测试对于排除PHPT在这些特定的临床场景中至关重要.
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