对慢性咳和喉回流之间关系的叙述性综述
Viktória Hránková1,2, Tomáš Balner3,4, Patrícia Gubová1
1Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital of Ostrava, Ostrava, Czechia.
Frontiers in medicine
|May 6, 2024
概括
喉回流 (LPR) 是慢性咳的关键原因,通常没有典型的GERD症状. 诊断涉及MII-pH监测,治疗从改变生活方式和PPI开始.
科学领域:
- 胃肠病学 胃肠病学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 肺部病理学 肺部病理学
背景情况:
- 胃食道逆流性疾病 (GERD) 是已知的慢性咳的原因之一.
- 许多患有食道外症状的患者缺乏典型的GERD症状,并且内镜检查正常.
- 喉喉反流 (LPR) 描述了影响喉和喉的反流,通常没有典型的GERD症状.
研究的目的:
- 审查和总结有关慢性咳和LPR之间关系的当前知识.
- 整合过去13年发表的研究信息.
- 突出诊断和治疗方面的挑战以及未来的研究方向.
主要方法:
- 对过去13年出版的信息进行文献综述.
- 专注于研究LPR作为慢性咳的原因.
- 包括诊断方法,如24小时多通道内阻抗-pH (MII-pH) 监测.
主要成果:
- 喉回流 (LPR) 在20%的慢性咳患者中被发现.
- 24小时多通道内阻抗-pH (MII-pH) 监测是LPR的主要诊断工具.
- 通过MII-pH监测检测到的反流发作可以刺激上下呼吸道粘膜.
结论:
- 慢性咳是一种重要的,经常被忽视的,无法解释的慢性咳的原因.
- 治疗通常以改变生活方式和饮食改变开始,随后是质子抑制剂 (PPI) 治疗.
- 进一步的研究对于改善诊断生物标志物,了解非酸性反流和开发向疗法至关重要.
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