带有酸和没有酸的白银二胺化物对Streptococcus mutans的抗菌作用
Carlos Alonso Alvarez-Marín1, Norma Leticia Robles-Bermeo1, Wael Hegazy Hassan Moustafa2
1The Advanced Studies and Research Center in Dentistry Dr. Keisaburo Miyata, School of Dentistry, The Autonomous University of the State of Mexico, Toluca, Mexico.
Contemporary clinical dentistry
|May 6, 2024
概括
银胺化物 (SDF) 有效地对抗突变性菌株,但添加酸 (KI) 会降低其抗菌能力. 无论是SDF还是KI,都能单独实现完全的细菌抑制.
科学领域:
- 牙损伤的预防和治疗 牙损伤的预防和治疗
- 牙科材料的抗菌有效性 牙科材料的抗菌有效性
背景情况:
- 银二胺化物 (SDF) 是一种局部药物,用于治疗病变和预防新的病变.
- 化 (KI) 有时与SDF一起使用,以减轻染色和保持抗菌作用.
研究的目的:
- 为了比较单独的SDF与与KI结合的SDF的抗菌作用.
- 评估对Streptococcus mutans和牙科生物膜的影响.
主要方法:
- 使用抑制光环,最小抑制效应 (MIE) 和殖民地形成单元 (CFU) 试验评估的抗菌活性.
- 测试了SDF,KI及其对S. mutans的组合.
主要成果:
- 在10%度下,SDF表现出抗菌作用,明显高于KI (P=0.001).
- 所有测试物质 (SDF,KI,SDF+KI) 在CFU测试中实现了S. mutans的完全抑制.
- 将KI添加到SDF中减少了SDF的抗菌能力.
结论:
- SDF对S. mutans非常有效,即使在低度下也是如此.
- 虽然SDF和KI都表现出抗菌性质,但它们的结合会降低SDF的有效性.
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