多发性骨髓瘤死亡率的差异 美国人口状况的死亡率趋势
Sishir Doddi1, M Hammad Rashid2
1Department of Medicine, University of Toledo College of Medicine, Toledo, OH, U.S.A.
Cancer diagnosis & prognosis
|May 6, 2024
概括
从1999年到2020年,美国多发性骨髓瘤 (MM) 的死亡率总体下降,但人口群体之间仍然存在显著差异,黑人和非洲裔美国人死亡率更高. 需要针对风险人群进行有针对性的研究和资源.
科学领域:
- 血液学 血液学 血液学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 多发性骨髓瘤 (MM) 是一种血细胞恶性瘤.
- 了解MM死亡率的人口差异和时间趋势对于公共卫生倡议至关重要.
研究的目的:
- 评估多发性骨髓瘤死亡率的人口差异.
- 从1999年到2020年分析多发性骨髓瘤死亡率的时间趋势.
主要方法:
- 利用疾病预防控制中心的WONDER数据库进行流行病学数据.
- 分析了年龄调整的死亡率 (AAMR) 和年平均百分比变化 (AAPC).
- 在各种人口群体中比较死亡率趋势,包括性别,种族和种族.
主要成果:
- 总体而言,美国MMMM死亡率在1999年至2020年期间下降.
- 观察到显著的差异:黑人和非洲裔美国人拥有最高的AAMR (2020年为55.6).
- 与男性相比,女性的AAMR下降率更高. 在亚裔美国人和太平洋岛民,美洲印第安人/阿拉斯加原住民和黑人/非洲裔美国人群体之间注意到了下降趋势的显著差异.
结论:
- 这些发现突出了特定人群的MM死亡风险较高.
- 确定有针对性的资源分配和进一步研究以解决差异的领域.
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