基础和翻译研究在照顾拉丁美洲患有恶性固体瘤的儿童方面的重要性
María Belen Cancela1, Milagros Dinardi1, Rosario Aschero2
1Unidad de Tratamientos Innovadores Hospital de Pediatría JP Garrahan Buenos Aires Argentina Unidad de Tratamientos Innovadores, Hospital de Pediatría JP Garrahan, Buenos Aires, Argentina.
概括
拉丁美洲的儿童癌症研究取得了进展,阿根廷,巴西和墨西哥的出版物领先. 加强国际和区域合作对于开发针对儿童固体瘤和脑癌的新疗法至关重要.
科学领域:
- 在瘤学瘤学.
- 翻译研究是翻译研究.
- 儿科恶性瘤 儿童恶性瘤
背景情况:
- 儿童癌症的基础和转化研究对于改善患者护理至关重要.
- 拉丁美洲在儿科瘤学研究开发方面面临着挑战.
研究的目的:
- 系统地审查2013年至2023年间拉丁美洲儿科癌症基础和翻译研究的发展情况.
- 确定关键的研究领域,出版趋势和合作模式.
主要方法:
- 系统审查PubMed索引英语出版的原始文章 (2013-2023年).
- 包括拉丁美洲研究人员对儿科恶性固体和中枢神经系统瘤的研究,包括国际合作.
- 排除仅针对成人癌症或一般瘤生物学而没有特定相关性的研究.
主要成果:
- 分析了514篇文章,主要来自阿根廷,巴西和墨西哥.
- 来自阿根廷,巴西和墨西哥与欧洲和北美的国际合作数量最高.
- 骨肉瘤,神经母细胞瘤和髓母细胞瘤是最受研究的;分子分析,细胞生物学和生物标志物是关键研究领域.
结论:
- 儿科瘤学研究在拉丁美洲活跃,但出版和协作存在差异.
- 需要在拉丁美洲和全球范围内加强科学合作.
- 开发针对拉丁美洲儿童固体瘤和脑癌的当地需求量身定制的新型治疗策略至关重要.
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