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Updated: Jun 27, 2025

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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通过加热将印-3-碳醇转化为具有抗黑色素瘤作用的N替代的寡合体

Jia Cheng Qian1, Heng Peng Zhang1, Yi Wang1

  • 1State Key Laboratory Cultivation Base for TCM Quality and Efficacy, Nanjing University of Chinese Medicine, Nanjing 210023, PR China.

Food chemistry: X
|May 6, 2024
PubMed
概括

加热十字花蔬菜将英多尔-3-碳醇 (I3C) 转化为独特的英多尔衍生物. 一种新型化合物DIM-1显示出作为抗癌药物候选药物的潜力.

关键词:
这是一种抗黑色素瘤药物.化学合成 化学合成十字花的蔬菜是一种十字花的蔬菜.印度尔3 - 碳醇.N-(醇-3-甲基) - 3,3′-二醇甲.

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Compounds bearing two hydroxyl groups are known as diols. When the hydroxyl groups are located on adjacent carbon atoms, the diols are called vicinal diols or glycols. Under acidic conditions, vicinal diols undergo a specific reaction called pinacol rearrangement.
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