住院患者对参加随机对照试验的态度,以应对心脏骤停的情况
Malin Albert1, Marie Thonander2,3, Sune Forsberg1,4
1Department of Clinical Science and Education, Södersjukhuset, Centre for Resuscitation Science, Karolinska Institutet, Sweden.
Resuscitation plus
|May 6, 2024
概括
大多数住院患者愿意参加心脏骤停临床试验. 参与心脏骤停 (VAST-A) 试验的首要动机是为医学研究做出贡献.
科学领域:
- 临床研究 临床研究
- 心脏病学 心脏病学
- 紧急医疗 紧急医疗
背景情况:
- 之前的研究还没有评估患者对参与心脏骤停临床试验的态度.
- 这项研究旨在评估患者在心脏骤停 (VAST-A) 试验中除上腺素外的血管压迫素和类固醇的意愿和动机.
研究的目的:
- 评估患者是否愿意参加住院心脏骤停 (IHCA) 临床试验.
- 了解患者批准或拒绝参与试验的动机.
主要方法:
- 住院患者在住院期间为潜在的纳入VAST-A试验提供了知情同意.
- 患者接受了关于他们参与意愿,同意决定的原因和基线特征的调查.
主要成果:
- 在接受调查的1064名患者中,有902人 (84.8%) 同意参加VAST-A试验.
- 对于411名患者的小组,批准的主要原因是为研究做出贡献 (83.9%).
- 对药物治疗测试的担忧是参与率下降的主要原因 (30%).
结论:
- 大多数住院患者愿意提供知情同意,以便纳入心脏骤停药物试验.
- 患者愿意参与临床试验的原因主要是希望推动医学研究.
相关概念视频
01:11Blinding
2.4K
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
2.4K
03:20The Stanford Prison Experiment
23.2K
The famous and controversial Stanford Prison Experiment, conducted by social psychologist Philip Zimbardo and his colleagues at Stanford University, demonstrated the power of social roles, social norms, and scripts.
23.2K