长期护理机构中多重治疗患者的潜在不合适的处方:回顾性药物利用分析
Roberta Giacometti1, Antonella Barbieri2, Maddalena Galante1
1Pharmacist in Local Health Authority of Vercelli.
概括
在长期护理机构的老年患者中,多药性是常见的,导致潜在的不适当药物 (PIM) 和药物相互作用. 定期检查药物和停止处方可以降低这些风险和医疗保健成本.
科学领域:
- 老年学是一门学科.
- 临床药房 临床药房
- 药物监督 药物监督 药物监督
背景情况:
- 长期护理 (LTC) 设施中的老年患者经常经历多药 (使用多种药物).
- 潜在不合适的药物 (PIM) 和药物相互作用 (DDI) 是这一群体的重大关注点.
- 多药房,PIM和住院/急诊室 (ED) 访问之间的联系需要调查.
研究的目的:
- 在老年LTC居民中调查PIM和潜在的药物相互作用.
- 确定这些问题是否与住院或急救访问有关.
- 评估药物管理策略的有效性.
主要方法:
- 对65岁以上患者在LTC设施中处方药物的分析 (2023年1月至7月).
- 利用月度药物处方数据库并应用Beers和STOPP标准来识别PIM.
- 检查了药物相互作用,并探索了与ED访问和不良药物反应 (ADR) 的联系.
主要成果:
- 多药和高多药的流行率很高 (分别为83%和17%).
- 最常见的PIM包括质子抑制剂,抗血小板剂和硫胺.
- 常见的相互作用药物是罗西米德,塞特拉林,潘托普拉和特拉佐. 没有病例将多药与ED访问或ADR联系在一起.
结论:
- 老年LTC居民的多药性增加了PIM和ADR的风险.
- 定期的治疗方案审查和减缓处方对于减少不适当的药物使用,相互作用和ED访问至关重要.
- 这些干预措施可以使医疗保健支出大幅减少.
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