选择的缺点:仪器控制增加了有条件的nocebo过敏症
Biya Tang1, Evan Livesey, Ben Colagiuri
1School of Psychology, The University of Sydney, Sydney, Australia.
Pain
|May 6, 2024
概括
治疗选择可能会恶化nocebo过敏症,增加疼痛而不是减少它. 提供关于选择的积极信息并没有抵消这种效应,建议在使用选择来管理疼痛结果时谨慎使用.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 疼痛研究 疼痛研究
背景情况:
- 负面期望加剧疼痛的nocebo过敏症是一个重要的临床挑战.
- 缓解nocebo效应的伦理策略对于患者护理至关重要.
- 以前的研究表明,选择减少了副作用,但其对nocebo过敏症的影响尚不清楚.
研究的目的:
- 为了研究选择对有条件的nocebo过敏症的影响.
- 为了确定关于选择的积极信息是否可以抵消增加的nocebo过敏症.
主要方法:
- 使用电皮疼痛模式,假装设备激活与有害刺激相结合.
- 研究1:健康的志愿者 (N=104) 被随机分配到有选择,没有选择或自然史控制的组.
- 研究2:健康的成年人 (N=137) 接受了可选择和积极信息的nocebo治疗,只有选择,或没有选择.
主要成果:
- 与没有选择相比,选择显著增加了nocebo过敏症在研究1中.
- 在研究2中,关于选择的积极信息未能减少增加的nocebo过敏症.
- 结果表明,治疗选择可能会在nocebo环境中加剧疼痛.
结论:
- 与预期相反,提供治疗选择可能会恶化nocebo过敏症和疼痛结果.
- 使用选择来减轻nocebo效应的策略需要仔细考虑,可能不会普遍有益.
- 需要进一步的研究来理解选择,期望和疼痛感知之间的复杂相互作用.
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