在立陶宛的性脑炎后长期的神经和神经认知障碍 - - 一项前性研究
Vytautas Griška1, Aistė Pranckevičienė2, Jolita Pakalnienė1
1Department of Infectious Diseases, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Infectious diseases (London, England)
|May 6, 2024
概括
在性脑炎 (TBE) 后,长期的神经和认知缺陷很常见,即使在轻微的情况下也是如此. 这些障碍,特别是在处理速度和学习方面,在许多TBE幸存者中持续超过一年.
科学领域:
- 神经学 神经学
- 神经科学是一个神经科学.
- 传染性疾病 传染性疾病
背景情况:
- 传染性脑炎 (TBE) 是一种严重的神经疾病.
- 了解长期后果对于患者管理至关重要.
研究的目的:
- 在成年人中特征TBE后的长期神经和神经认知后果.
- 评估疾病严重程度对结果的影响.
主要方法:
- 98名TBE患者在感染后18个月内进行了神经和神经认知功能评估.
- 评估包括格拉斯哥结果尺度 (GOS),兰金尺度 (RS),修改的兰金尺度 (MRS) 和矩阵共识认知电池 (MCCB).
- 认知数据与年龄,性别和教育相匹配的健康对照进行了比较.
主要成果:
- 超过20%的患者在TBE后长达18个月的持续残疾.
- 在6个月后,与对照组相比,TBE患者在处理速度,口头和视觉学习方面表现出显著的缺陷.
- 即使在轻微的TBE病例中也注意到认知障碍,并且因年龄组而异.
结论:
- 在TBE之后,长期的神经和神经认知缺陷很普遍.
- 损伤影响多个认知领域,即使在轻微的TBE后也可能发生.
- 年轻的患者和轻度TBE患者可能会遇到特定的认知挑战.
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